Effects of various weight-reducing drugs on eating behavior

Introduction . Eating disorders (ED) in obese patients dramatically reduce adherence to treatment and its effectiveness, which determines the importance of correcting ED. Aim To evaluate presence various types eating behavior (EB) patients, effect sibutramine liraglutide on EB, hunger satiety optimize individual choice. Materials methods The study included 53 (BMI over 30 kg/m2), whom 17 received (3.0 mg/ day) 36 – (10 mg/day). type EB was determined using Dutch Behavior Questionnaire (DEBQ). survey conducted before after 6 months continuous treatment. VAS scale used assess appetite. Results decrease body weight, BMI, waist hip circumference statistically significant comparable groups (p < 0.001 for all parameters both groups). Sibutramine showed a emotional (EmEB) = 0.003), had no EmEB. Treatment with increased severity restrained (REB) 0.002); group liraglutide, there only tendency score REB 0.109). Liraglutide did not lead changes external (ExEB). Therapy equally led reduction amount food eaten. Conclusions similar weight effect, but they have different effects indicators. Patients EmEB may benefit more from than liraglutide. pronounced violation is patient, difficult it correlate. Questionnaires, example DEBQ, can be an choice method.